As men age, the amount of testosterone in their bodies gradually declines. Although a direct cause and effect relationship between testosterone deficiency and erectile dysfunction has not been proven, decreased testosterone levels in patients with erectile dysfunction have been observed in clinical settings. Atherosclerosis (hardening of the arteries) Stress, anxiety, or depression Alcohol or tobacco use Some prescription medicines Tiredness Brain or spinal cord damage Low testosterone Multiple sclerosis Parkinson’s disease Radiation therapy to the testicles Stroke Some types of prostate or bladder surgery
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O'Donnell AB, Araujo AB, McKinlay JB. The health of normally aging men: The Massachusetts Male Aging Study (1987–2004). Exp Gerontol 2004; 39: 975–84.
Sildenafil is our most popular erectile dysfunction treatment due to its clinically proven effects and affordable price. It works by establishing reliable blood flow to the penis, ensuring a strong erection when you need one.
Phosphodiesterase-5 (PDE-5) inhibitors, such as sildenafil, tadalafil and vardenafil, are among the most widely used and effective drugs for the treatment of ED. They work by temporarily increasing the blood supply to the penis (Table 4).
In cases of underlying conditions resulting in erectile dysfunction, treating the underlying condition can help reverse the dysfunction.
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14. Evans JD, Hill SR. A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil. Patient Preference and Adherence. 2007;9:1159-1164.
Avanafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil (Viagra) or other drugs similar to avanafil. Most of these people also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether avanafil is the actual cause of vision loss.
There are several treatments for erectile dysfunction. Your doctor can advise you on the benefits and drawbacks of each.
With BlueChew, you save on a per-month subscription for tadalafil as compared to Hims and other telemedicine providers. Right now, you can try a free month of BlueChew tadalafil. We are not sure how long this opportunity will last. The most economical major treatment Has been the subject of the most studies High rate of effectiveness Allows easy flexibility in dosage The window of effectiveness requires a bit of planning Loses efficacy when you take it with meals In studies, mild side effects like headache are more common than with other treatments like Stendra
Pharmalogic TreatmentPharmacologic options for treatment of ED include oral phosphodiesterase type 5 inhibitors (PDE5Is) or intraurethral or intracavernosal injection alprostadil.6 Intracavernosal nonprostaglandin agents such as papaverine, phentolamine, and atropine have also been used to successfully manage ED, but none are FDA-approved for this indication. Testosterone replacement may also be considered for men with hypogonadism.6
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Preference for Viagra isn’t just a sugar-pill thing, either; there are differences in dosage to consider. Viagra commonly comes in 25mg, 50mg, and 100mg doses, with a typical dose of 50mg prescribed at the outset for men under 65. Sildenafil, meanwhile, comes in a broader range of options, including 20, 30, 35, 60, 80, and 100 mg. So, it’s the same active ingredient (sildenafil), which acts in the same way in the male body. But you may experience different levels of efficacy and side effects depending on the dosage.
If you are being treated for both benign prostatic enlargement and erectile dysfunction, the dose is 5mg.
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