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The most common sexual problem facing men living in the United States is erectile dysfunction — which affects about 30 million men in the U.S. (1) Erectile dysfunction can greatly affect a man’s quality of life and his relationship with his partner. Plus, research shows that many patients with erectile dysfunction also have signs of depression and anxiety that’s related to disappointment about their sexual performance. (2)

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As men age, the amount of testosterone in their bodies gradually declines. Although a direct cause and effect relationship between testosterone deficiency and erectile dysfunction has not been proven, decreased testosterone levels in patients with erectile dysfunction have been observed in clinical settings. Atherosclerosis (hardening of the arteries) Stress, anxiety, or depression Alcohol or tobacco use Some prescription medicines Tiredness Brain or spinal cord damage Low testosterone Multiple sclerosis Parkinson’s disease Radiation therapy to the testicles Stroke Some types of prostate or bladder surgery
Black and Latino Seniors Commonly Experience Healthcare Discrimination, Report Says .

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O'Donnell AB, Araujo AB, McKinlay JB. The health of normally aging men: The Massachusetts Male Aging Study (1987–2004). Exp Gerontol 2004; 39: 975–84.
Sildenafil is our most popular erectile dysfunction treatment due to its clinically proven effects and affordable price. It works by establishing reliable blood flow to the penis, ensuring a strong erection when you need one.

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Phosphodiesterase-5 (PDE-5) inhibitors, such as sildenafil, tadalafil and vardenafil, are among the most widely used and effective drugs for the treatment of ED. They work by temporarily increasing the blood supply to the penis (Table 4).
In cases of underlying conditions resulting in erectile dysfunction, treating the underlying condition can help reverse the dysfunction.

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Benign Prostatic Hyperplasia/BPH, Erectile Dysfunction, General Urology, Male Incontinence, Male Sexual Dysfunction, Peyronie's Disease, Urethral Stricture Disease, UroLift

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All men receiving testosterone replacement need to have periodic measurement of haemoglobin and haematocrit to monitor for erythrocytosis. Feldman HA , Goldstein I , Hatzichristou DG , et al . Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54–61. Araujo AB , Esche GR , Kupelian V , et al . Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab 2007;92:4241–7. doi:10.1210/jc.2007-1245 Lindau ST , Schumm LP , Laumann EO , et al . A study of sexuality and health among older adults in the United States. N Engl J Med 2007;357:762–74. doi:10.1056/NEJMoa067423 Shah J . Erectile dysfunction through the ages. BJU Int 2002;90:433–41. doi:10.1046/j.1464-410X.2002.02911.x Mobley D . Early history of inflatable penile prosthesis surgery. Asian J Androl 2015;17:225–9. Roumeguère T , Wespes E , Carpentier Y , et al . Erectile Dysfunction is associated with a high prevalence of hyperlipidemia and coronary Heart Disease Risk European Urology.44:355–9. Klein R , Klein BE , Lee KE , et al . Prevalence of self-reported erectile dysfunction in people with long-term IDDM. Diabetes Care 1996;19:135–41. doi:10.2337/diacare.19.2.135 Larsen SH , Wagner G , Heitmann BL . Sexual function and obesity. Int J Obes 2007;31:1189–98. doi:10.1038/sj.ijo.0803604 McWaine DE , Procci WR . Drug-induced sexual dysfunction. Med Toxicol Adverse Drug Exp 1988;3:289–306. doi:10.1007/BF03259941 Croft H , Settle E , Houser T , et al . A placebo-controlled comparison of the antidepressant efficacy and effects on sexual functioning of sustained-release bupropion and sertraline. Clin Ther 1999;21(4):643–58. doi:10.1016/S0149-2918(00)88317-4 Janeway M , Baum N . Managing the enlarged prostate gland in elderly men. Clinical Geriatrics http://www.consultant360.com/articles/managing-enlarged-prostate-gland-elderly-men. Kumar RJ , Barqawi A , Crawford ED . Adverse events associated with hormonal therapy for prostate Cancer. Rev Urol 2005;7 Suppl 5:S37–S43. Aksam A , Yassin A , Saad F . Testosterone and erectile dysfunction. J Andrology 2008;29. Gades NM , Nehra A , Jacobson DJ , et al . Association between smoking and erectile dysfunction: a population-based study. Am J Epidemiol 2005;161:346–51. doi:10.1093/aje/kwi052 Mobley D , Baum N . Smoking: it’s impact on urologic conditions. Rev Urology 17 2015. Stein RA . Endothelial dysfunction, erectile dysfunction, and coronary heart disease: the pathophysiologic and clinical linkage. Rev Urol 2003;5(Suppl 7):S21–S27. Andersson K , Stief C . Penile erection and cardiac risk: pathophysiologic and pharmacologic mechanisms. Am J Cardiol 2000;86:23–6. doi:10.1016/S0002-9149(00)00887-0 Feldman HA , Johannes CB , Derby CA , et al . Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev Med 2000;30:328–38. doi:10.1006/pmed.2000.0643 Vlachopoulos C , Ioakeimidis N , Terentes-Printzios D , et al . The triad: erectile dysfunction-endothelial dysfunction-cardiovascular disease Curr Pharm Des. 2008;14:3700–14. Watts GF , Chew KK , Stuckey BG et al . The erectile-endothelial dysfunction nexus: new opportunities for cardiovascular risk prevention. Nat Clin Pract Cardiovasc Med 2007;4:263–73. doi:10.1038/ncpcardio0861 Montorsi F , Briganti A , Salonia A , et al . Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease. Eur Urol 2003;44:360–5. doi:10.1016/S0302-2838(03)00305-1 Vlachopoulos C , Rokkas K , Ioakeimidis N , et al . Prevalence of asymptomatic coronary artery disease in men with vasculogenic erectile dysfunction: a prospective angiographic study. Eur Urol 2005;48:996–1003. doi:10.1016/j.eururo.2005.08.002 Mulhall J , Teloken P , Barnas J et al . Vasculogenic erectile dysfunction is a predictor of abnormal stress echocardiography. J Sex Med 2009;6:820–5. doi:10.1111/j.1743-6109.2008.01087.x Hodges LD , Kirby M , Solanki J , et al . The temporal relationship between erectile dysfunction and cardiovascular disease. Int J Clin Pract 2007;61:2019–25. doi:10.1111/j.1742-1241.2007.01629.x Inman BA , Sauver JL , Jacobson DJ , et al . A population-based, longitudinal study of erectile dysfunction and future coronary artery disease. Mayo Clin Proc 2009;84:108–13. doi:10.4065/84.2.108 Ponholzer A , Temml C , Obermayr R , et al . Is erectile dysfunction an indicator for increased risk of coronary heart disease and stroke? Eur Urol 2005;48:512–8. doi:10.1016/j.eururo.2005.05.014 Thompson IM , Tangen CM , Goodman PJ , et al . Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005;294:2996–3002. doi:10.1001/jama.294.23.2996 Banks E , Joshy G , Abhayaratna WP , et al . Erectile dysfunction severity as a risk marker for cardiovascular disease hospitalisation and all-cause mortality: a prospective cohort study. PLoS Med 2013;10:e1001372. doi:10.1371/journal.pmed.1001372 Lewis RW , Fugl-Meyer KS , Corona G , et al . Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med 2010;7:1598–607. doi:10.1111/j.1743-6109.2010.01778.x Yaman O , Gulpinar O , Hasan T , et al . Erectile dysfunction may predict coronary artery disease: relationship between coronary artery calcium scoring and erectile dysfunction severity. Int Urol Nephrol 2008;40:117–23. doi:10.1007/s11255-007-9293-8 Montorsi P , Ravagnani PM , Galli S , et al . Association between erectile dysfunction and coronary artery disease. role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial. Eur Heart J 2006;27:2632–9. doi:10.1093/eurheartj/ehl142 Montorsi P , Ravagnani PM , Galli S , et al . Association between erectile dysfunction and coronary artery disease:matching the right target with the right test in the right patient. Eur Urol 2006;50:721–31. doi:10.1016/j.eururo.2006.07.015 Yassin AA , Saad F . Testosterone and erectile dysfunction. J Androl 2008;29:593–604. doi:10.2164/jandrol.107.004630 Khera M . Androgens and erectile function: a case for early androgen use in postprostatectomy hypogonadal men. J Sex Med 2009;6:234–8. doi:10.1111/j.1743-6109.2008.01159.x Aversa A , Isidori AM , De Martino MU , et al . Androgens and penile erection: evidence for a direct relationship between free testosterone and cavernous vasodilation in men with erectile dysfunction. Clin Endocrinol 2000;53:517–22. doi:10.1046/j.1365-2265.2000.01118.x Wespes E , Amar E , Hatzichristou D , et al . EAU guidelines on erectile dysfunction: an update. Eur Urol 2006;49:806–15. doi:10.1016/j.eururo.2006.01.028

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    It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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    Erectile dysfunction (ED) is one of the most common conditions affecting middle-aged and older men. Nearly every primary care physician, internist and geriatrician will be called upon to manage this condition or to make referrals to urologists, endocrinologists and cardiologists who will assist in the treatment of ED. This article will briefly discuss the diagnosis and management of ED. In addition, emerging concepts in ED management will be discussed, such as the use of testosterone to treat ED, the role of the endothelium in men with ED and treating the partner of the man with ED. Finally, future potential therapies for ED will be discussed.

    14. Evans JD, Hill SR. A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil. Patient Preference and Adherence. 2007;9:1159-1164.
    Avanafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil (Viagra) or other drugs similar to avanafil. Most of these people also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether avanafil is the actual cause of vision loss.

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    ED tablets should not be taken more than once a day. Taking any ED treatment more than once a day will increase the risk of experiencing side effects. If you'd prefer the freedom to have more frequent sex, you may want to try tadalafil or Tadalafil Daily. These ED medications last for a long period of time and give you more flexibility to enjoy spontaneous sex without needing to wait 24 hours to take another tablet.

    There are several treatments for erectile dysfunction. Your doctor can advise you on the benefits and drawbacks of each.
    With BlueChew, you save on a per-month subscription for tadalafil as compared to Hims and other telemedicine providers. Right now, you can try a free month of BlueChew tadalafil. We are not sure how long this opportunity will last. The most economical major treatment Has been the subject of the most studies High rate of effectiveness Allows easy flexibility in dosage The window of effectiveness requires a bit of planning Loses efficacy when you take it with meals In studies, mild side effects like headache are more common than with other treatments like Stendra

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    GAINSWave therapy is effective and safe for men who cannot take oral ED medicine, such as those with heart disease, diabetes, or high blood pressure. GAINSWave can be used to treat Peyronie’s Disease, which Viagra and other oral ED drugs cannot. About Menu Toggle What is GAINSWave ? What to Expect? How it Works? Comparing Treatments FAQs Medical Advisory Board Expected Results Menu Toggle Erectile Dysfunction Treatment Peyronie’s Disease Treatment Sexual Enhancement Clinical Research Testimonials Am I a Candidate? Testimonials Resources Menu Toggle Men’s Health Guide Provider Resources Magazine Press Become a Provider Find A Provider

    Pharmalogic TreatmentPharmacologic options for treatment of ED include oral phosphodiesterase type 5 inhibitors (PDE5Is) or intraurethral or intracavernosal injection alprostadil.6 Intracavernosal nonprostaglandin agents such as papaverine, phentolamine, and atropine have also been used to successfully manage ED, but none are FDA-approved for this indication. Testosterone replacement may also be considered for men with hypogonadism.6
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Preference for Viagra isn’t just a sugar-pill thing, either; there are differences in dosage to consider. Viagra commonly comes in 25mg, 50mg, and 100mg doses, with a typical dose of 50mg prescribed at the outset for men under 65. Sildenafil, meanwhile, comes in a broader range of options, including 20, 30, 35, 60, 80, and 100 mg. So, it’s the same active ingredient (sildenafil), which acts in the same way in the male body. But you may experience different levels of efficacy and side effects depending on the dosage.

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If you are being treated for both benign prostatic enlargement and erectile dysfunction, the dose is 5mg.

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U.S. Food and Drug Administration. FDA Drug Safety Communication: fda cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke with use. www.fda.gov/Drugs/DrugSafety/ucm436259.htm. Bassil N , Alkaade S , Morley JE . The benefits and risks of testosterone replacement therapy: a review. Ther Clin Risk Manag 2009;5:427–48. Søe KL , Søe M , Gluud C . Liver pathology associated with the use of anabolic-androgenic steroids. Liver 1992;12:73–9. doi:10.1111/j.1600-0676.1992.tb00560.x Randrup E , Baum N , Feibus A . Erectile dysfunction and cardiovascular disease. Postgrad Med 2015;127:166–72. doi:10.1080/00325481.2015.992722 Wrishko R , Sorsaburu S , Wong D , et al . Safety, efficacy, and pharmacokinetic overview of low-dose daily administration of tadalafil. J Sex Med 2009;6:2039–48. doi:10.1111/j.1743-6109.2009.01301.x Seftel AD , Sun P , Swindle R . The prevalence of hypertension, Hyperlipidemia, diabetes mellitus and depression in men with erectile dysfunction. J Urol 2004;171:2341–5. doi:10.1097/01.ju.0000125198.32936.38

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