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Avanafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil (Viagra) or other drugs similar to avanafil. Most of these people also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether avanafil is the actual cause of vision loss. .
Causes of ED are usually a side effect of physical disease, injury, or drugs. While there are many causes, the most common physical causes include: Diabetes High Blood Pressure Heart Disease Obesity Atherosclerosis Prescription Medications Smoking Alcoholism or Substance Abuse Relationship Issues Stress Depression or Anxiety Diagnosis
Inman BA, Sauver JL, Jacobson DJ, et al. A population-based, longitudinal study of erectile dysfunction and future coronary artery disease. Mayo Clin Proc 2009; 84: 108–13.
“If someone really wants an herbal supplement, I’ll recommend ginseng,” Laborde says. “At least it’s not going to hurt you.”
Erectile dysfunction (ED) is the inability to get or maintain an erection hard enough for satisfactory sex. The causes of ED can be psychological or physical and usually result in reduced blood flow to the penis - making it harder to get an erection.
Watts and coworkers, in their review article, make several points about this ED/CAD nexus. Endothelial dysfunction is present in both CVD and ED, and is linked through the NO mechanism. The authors note that PDE5 inhibitors improve endothelial function and have a salutary effect on both CVD and ED. Both ED and cardiac disease respond to modifications in lifestyle as well as pharmacologic manipulation. These authors also report that the presence of ED gives the clinician an opportunity to assess CVD and prevention as well.20
Grapefruit may interact with sildenafil and lead to unwanted side effects. Avoid the use of grapefruit products.
19. Staxyn (Vardenafil) [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; August 2017.
Patients can find ED to be a very difficult subject and outright, initial declaration of their problem a huge barrier to diagnosis and treatment (and this might also depend on the gender of the doctor or the patient's relationship with them).2
The Sexual Advice Association has factsheets on medicines and other treatments for erectile dysfunction.
The side effects of ED medicine are mostly the same. Sildenafil and vardenafil can cause: Headache. Flushing (face and upper body turning red and warm). Stomach upset. Runny nose (sniffles). vision changes (things look blue).
In response, a number of erectile dysfunction treatments have been developed, with varying efficacy and side effects.
Though erectile dysfunction treatment options may include ED medication and surgery, there are also noninvasive erectile dysfunction remedies that may help.
Many factors can contribute to sexual dysfunction in older men, including physical and psychological conditions, comorbidities and the medications used to treat them. Aspects of an ageing man’s lifestyle and behaviour and androgen deficiency, most often decreasing testosterone levels, may affect sexual function as well. A study of men between the ages of 30 and 79 years showed that 24% had testosterone levels below 300 ng/dL and 5.6% had symptomatic androgen deficiency.2
Low testosterone levels can have an impact on libido (sex drive), which may cause erectile issues in some men. This is...
Men presenting with ED should have consideration for a cardiovascular work-up as significant numbers of these men have occult or asymptomatic heart or vascular disease.